Clinical & Molecular Biomedicine (CMB) welcomes submissions of original, high-quality manuscripts that advance molecular and clinical biomedical research. Authors are required to prepare manuscripts according to the journal’s formatting, ethical, and reporting standards before submission.

Authors should ensure that their work is original, unpublished, and not under consideration by another journal at the time of submission.

Clinical & Molecular Biomedicine accepts the following categories of manuscripts:

Original Research Articles

Full-length reports describing novel experimental or clinical findings.

Review Articles

Comprehensive and critical reviews summarizing current knowledge in a specific field.

Short Communications

Brief reports presenting important preliminary findings.

Case Reports

Clinical observations offering novel insights into disease or treatment.

Methods and Protocols

Descriptions of new techniques or improved experimental methodologies.

Letters to the Editor

Comments or discussions related to previously published articles.

Authors should submit manuscripts through the journal’s online submission system.

Submit Manuscript: Submit Manuscript

Authors must follow the instructions provided on the submission page and upload all required files in the appropriate format.

Before submitting a manuscript, authors must ensure that:

• The manuscript is original and has not been published previously, except in the form of a preprint, abstract, published lecture, academic thesis, or registered report.

• The manuscript is not under consideration for publication elsewhere.

• All authors have approved the submission.

• The responsible authorities where the work was carried out have approved the submission, where applicable.

• If accepted, the article will not be published elsewhere in the same form without the written consent of the copyright holder.

A cover letter must accompany every submission. The cover letter should:

• Describe the scope, importance, and novelty of the manuscript.

• Disclose any potential competing interests.

• Confirm originality and exclusivity of submission to CMB.

• Acknowledge author contributions and funding sources.

• Suggest potential reviewers and optionally request exclusion of up to five reviewers.

• Provide complete contact details for all authors, clearly identifying the corresponding author.

Authors must provide editable source files for all components of the manuscript, including the main text, figures, tables, and graphical elements.

Manuscripts must be submitted in an editable format. Authors should use .doc or .docx for Microsoft Word files and .tex for LaTeX submissions.

PDF files are not accepted as source files for manuscript submissions.

Manuscripts prepared in Microsoft Word should use a single-column layout. Double-column formatting is permitted only for manuscripts prepared using LaTeX.

Before submission, authors should remove tracked changes, strikethrough text, and unnecessary underlining, unless such formatting is scientifically relevant.

Manuscripts should be submitted in Word format and prepared according to the following formatting guidelines:

• Use a normal, plain font, such as 12-point Times Roman.

• Use 1.5 line spacing.

• Use italics for emphasis only where necessary.

• Use automatic page numbering.

• Do not use field functions.

• Use tab stops or other formatting commands for indents, not the space bar.

• Use the table function to create tables, not spreadsheets.

• Use the equation editor or MathType for equations.

• Save the file in .docx format or .doc format.

Manuscripts should be organized in the following sections:

1. Title page
2. Abstract
3. Keywords
4. Introduction
5. Materials and Methods
6. Results
7. Discussion
8. Conclusions
9. Funding
10. Acknowledgments
11. References
12. Figure legends

Tables and figures

The title page should include the following information:

Article Title

The title should be concise, clear, and informative. Authors should avoid using abbreviations, symbols, or formulas.

Author Names

Authors should provide the full names of all authors, including given name(s) and family name(s). Names should be spelled correctly and appear in the same order as entered in the submission system.

Author Affiliations

Author affiliations should include the department or institution name, full postal address, country name, and email address, where available. Affiliations should be linked to authors using lower-case superscript letters.

Corresponding Author

The corresponding author must be clearly identified and will be responsible for communication with the journal during submission, peer review, publication, and post-publication correspondence. The corresponding author should provide a valid email address and contact details.

Present or Permanent Address

If an author has moved to a different institution after completing the research, the new address may be listed as a present or permanent address. The original institution where the work was performed should remain the main affiliation.

The abstract must be able to stand alone, as abstracts are often presented separately from the article.

The abstract should be 150–250 words and include:

• Background

• Methods

• Key results

• Conclusions

Authors should provide 4–6 keywords for indexing purposes.

Tables should be prepared in an editable text format and must not be submitted as images.

Tables should be clear, concise, and should present data without unnecessary duplication of information already described in the text or figures.

Authors should follow these guidelines:

• Tables must be numbered consecutively using Arabic numerals, such as Table 1 and Table 2.

• Each table must be cited in the manuscript text in sequential order.

• Tables should be placed close to the relevant text or on separate pages at the end of the document.

• Each table must include a clear and concise caption placed above the table.

• Previously published material must be acknowledged with a reference at the end of the table caption.

• Footnotes should be placed directly below the table body.

• Authors should avoid vertical lines, excessive formatting, and unnecessary cell shading.

Figures, images, diagrams, charts, graphs, and other graphical elements must be prepared with clarity, accuracy, and consistency.

All figures should be submitted as separate high-resolution files, in addition to being placed appropriately within the manuscript or at the end of the document.

Figure files should be named consecutively using the format Fig followed by the figure number, for example, Fig1.tiff or Fig2.eps.

Preferred file formats include:

• EPS or PDF for vector graphics, with all fonts embedded

• TIFF for halftone images or photographs

• JPG and PNG, provided that resolution requirements are met

• MS Office files, such as .docx or .pptx, only if figures are properly embedded and maintain adequate resolution

Minimum resolution requirements are:

• Photographs or halftone images: 300 dpi

• Combination figures with images and text or line elements: 500–600 dpi

• Line art: 1000–1200 dpi

Color images should be submitted in RGB format. Authors must ensure that figures remain clear and interpretable if converted to grayscale.

Authors should use standard sans-serif fonts such as Arial or Helvetica and maintain consistent font type and size across all figures.

Recommended font size is 8–12 pt after scaling. All text must remain legible after resizing for publication.

Figures must be numbered consecutively using Arabic numerals, such as Fig. 1 and Fig. 2, according to their order of appearance in the manuscript.

Figure captions must be provided in the main manuscript file, not inside the figure image. Each caption should include a concise title, a clear explanation of the figure content, and identification of all symbols, abbreviations, and graphical elements.

The use of generative artificial intelligence or AI-assisted tools to create or modify figures is generally not permitted.

An exception may be made when AI tools are used as part of the research methodology, such as biomedical image analysis or computational imaging. In such cases, authors must clearly describe the tool or model used, version details, and relevant technical parameters in the Methods section.

AI-generated artwork, including graphical abstracts or illustrations, requires prior editorial approval, appropriate disclosure, and attribution.

Authors may submit supplementary material to support and enhance the scientific content of their manuscripts.

Supplementary material may include extended datasets, additional figures and tables, high-resolution images, multimedia files, software, protocols, or other supporting information directly relevant to the study.

Supplementary files must be accurate, relevant, and clearly cited in the manuscript text. Authors must submit all supplementary files at the time of initial manuscript submission.

Supplementary files are published online as submitted, without copyediting, formatting, or typesetting by the journal production team. Authors are responsible for ensuring that these files are complete, accurate, clearly labeled, and suitable for publication.

Clinical & Molecular Biomedicine welcomes video files and animation sequences that enhance the presentation of scientific content.

Video and multimedia files must be clearly referenced within the manuscript text. Each file should have a descriptive filename and a concise explanation of its content.

Videos should be submitted in commonly accepted file formats and must not exceed 150 MB per file or 1 GB in total for all submitted multimedia files.

Authors must provide a representative still image for each video file.

The journal supports open, transparent, and reproducible research practices and strongly encourages authors to share research data wherever possible.

Research data may include experimental observations, datasets, computational models, software, code, protocols, and analytical outputs.

Authors are encouraged to deposit research data in a recognized public repository, cite and link datasets within the manuscript, and provide sufficient methodological and contextual information to allow reuse and verification.

If data sharing is not feasible, authors must provide a clear explanation, such as confidentiality, sensitivity, or patient-related restrictions.

Authors are encouraged to include a Data Availability Statement in the manuscript. The statement should clearly indicate where and how the data can be accessed, such as repository name, accession number, or persistent link.

If access is restricted, the statement should explain the reason for restriction.

Footnotes should be used sparingly and only where necessary. They should provide additional clarification that cannot be integrated into the main text without disrupting readability.

Footnotes must be numbered consecutively throughout the manuscript. Authors are encouraged to use the automatic footnote feature in word-processing software.

Authors may acknowledge individuals, institutions, or organizations that provided support during the research or preparation of the manuscript.

Acknowledgements may include language editing, proofreading, technical assistance, data collection support, or other non-author contributions.

The Acknowledgements section must be placed immediately before the reference list. Authors should ensure that acknowledged individuals have given permission to be named, where applicable.

Acknowledgements must not be included on the title page, as footnotes to the title, or in any other section of the manuscript.

For all submissions, the corresponding author must provide a detailed Author Contributions statement using the Contributor Roles Taxonomy (CRediT).

Common contribution roles include:

• Conceptualization

• Data curation

• Formal analysis

• Funding acquisition

• Investigation

• Methodology

• Project administration

• Resources

• Software

• Supervision

• Validation

• Visualization

• Writing – original draft

• Writing – review and editing

Not all roles will apply to every manuscript. Individual authors may contribute to multiple roles.

Authorship should reflect meaningful intellectual contributions to the research work, including study design, execution, analysis, or interpretation.

Authors must also participate in drafting or critically revising the manuscript, approve the final version, and agree to be accountable for all aspects of the work.

All submitted manuscripts must designate a corresponding author.

Requests to add, remove, or reorder authors after manuscript submission are strongly discouraged.

If changes are necessary, they must be justified in writing and approved by all listed authors, including authors being added or removed, before editorial consideration.

Once a manuscript has been formally accepted for publication, changes to authorship are generally not permitted.

Generative artificial intelligence tools, including large language models, cannot be listed as authors because they cannot assume responsibility or accountability for manuscript content.

If AI tools are used during manuscript preparation, such as for language editing or drafting assistance, their use must be clearly disclosed in the Methods, Acknowledgements, or another appropriate section.

Authors remain fully responsible for verifying the accuracy, integrity, and originality of all content.

The following statements must be included in the submitted manuscript under the heading Statements and Declarations.

This section should be placed after the References section.

Required statements may include:

• Declaration of competing interests

• Funding statement

• Ethics approval statement

• Informed consent statement

• Consent to publish statement

• Data availability statement, where applicable

• Author contributions statement

All authors must disclose any financial or personal relationships with individuals or organizations that could inappropriately influence, or be perceived to influence, their work.

If authors have no competing interests to declare, they should include the following statement:

“The authors declare that they have no competing interests.”

Authors must clearly disclose all sources of financial support received for the conduct of the research or preparation of the manuscript.

Authors should state the role of the funding organization or sponsor in study design, data collection, data analysis and interpretation, manuscript preparation, and the decision to submit the manuscript for publication.

If the funding source had no involvement, this should be explicitly stated.

All research involving human participants, human data, animals, or animal-derived materials must follow the highest ethical standards.

For human studies, authors must confirm that the study complied with the principles of the Declaration of Helsinki and received approval from an appropriate ethics committee or Institutional Review Board, where applicable.

For animal studies, authors must describe ethical care, handling, and use of animals in the Methods section.

If the study was exempt from ethical approval, this must be clearly stated and justified.

For studies involving human participants, authors must confirm that informed consent was obtained. For minors or vulnerable populations, consent must be obtained from parents or legal guardians.

If the manuscript includes identifiable individual data, such as images, videos, or case-specific details, authors must obtain explicit consent for publication.

The journal encourages the use of inclusive and respectful language in all manuscripts.

Authors should avoid language that implies superiority or bias based on age, gender, race, ethnicity, culture, sexual orientation, disability, or health condition.

Writing should be clear, neutral, respectful, and scientifically appropriate.

Research involving humans, animals, or eukaryotic cells should consider sex- and gender-based analyses when relevant.

Authors are encouraged to explain how sex and/or gender were considered in study design, data analysis, and interpretation of results. If such analyses were not conducted, authors should acknowledge any limitations in generalizability.

All references cited in the manuscript must be included in the reference list, and all references listed must be cited in the text.

Authors are responsible for ensuring consistency, accuracy, and completeness of all reference information.

References cited in the abstract must also be provided in full in the reference list.

Unpublished results and personal communications should generally not be included in the reference list. If such items are included, they should be clearly identified.

Authors are strongly encouraged to include Digital Object Identifiers (DOIs) wherever available.

Clinical & Molecular Biomedicine follows a numbered citation style.

References should be indicated by numbers in square brackets within the text and numbered consecutively in the order in which they first appear.

Example:

“…as previously reported [3,6]. Grubb and colleagues [8] obtained similar results.”

Journal titles should be abbreviated according to the List of Title Word Abbreviations.

Authors who wish to include previously published figures, tables, or text excerpts must obtain written permission from the original copyright holder before submission.

Permission must allow use of the material in both print and online formats of Clinical & Molecular Biomedicine.

Any reused material must be properly acknowledged in the manuscript, usually in the figure caption, table note, or relevant section of the text.

If permission documentation is not provided, the journal will assume that all submitted content is original and owned by the authors. Authors bear full responsibility for copyright issues related to reused material.

Authors are encouraged to ensure that the manuscript is written in clear, concise, and grammatically correct English.

Clear presentation improves fair and accurate evaluation by editors and reviewers.

After acceptance, authors will be required to complete a publishing agreement. The corresponding author will receive an email containing a secure link to the online agreement form.

Authors are encouraged to review copyright and licensing policies before completing the agreement.

Authors retain full copyright ownership of their work.

By choosing open access publication, authors agree to publish their article under a Creative Commons Attribution (CC BY) license, which permits redistribution, reuse, adaptation, and commercial use, provided that appropriate credit is given to the original authors and source.

Authors also grant the journal the right to publish, distribute, and promote the article under this license.

The proof stage is used to identify and correct typesetting, formatting, or conversion errors and to ensure the accuracy and completeness of the manuscript, including text, tables, and figures.

Substantial changes, such as adding new results, modifying data values, or changing the title or authorship, are not permitted at this stage without prior approval from the Editor.

Once the article is published online, further corrections can only be made through an Erratum formally linked to the original publication.

Accepted articles are published online shortly after corrected proofs are received.

The Online First version represents the official first publication and is fully citable using its Digital Object Identifier.

After inclusion in a scheduled issue, the article may also be cited using volume, issue, and page numbers.

All articles published in Clinical & Molecular Biomedicine are made available through a fully open-access model, ensuring immediate and unrestricted access to readers worldwide.

Currently, no article processing charges are required for publication.